GDF11 expressed in the adult brain negatively regulates hippocampal neurogenesis
Abstract Growth differentiation factor 11 (GDF11) is a transforming factor-β superfamily member that functions as a negative regulator of neurogenesis during embryonic development. However, when recombinant GDF11 (rGDF11) is administered systemically in aged mice, it promotes neurogenesis, the oppos...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BMC
2021-09-01
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| シリーズ: | Molecular Brain |
| 主題: | |
| オンライン･アクセス: | https://doi.org/10.1186/s13041-021-00845-z |
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