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HIF-1 α as a Key Factor in Bile Duct Ligation-Induced Liver Fibrosis in Rats

Background: Although several studies suggested hypoxia as an important microenvironmental factor contributing to inflammation and fibrosis in chronic liver diseases, the mechanism of this process is not fully understood. We considered hypoxia inducible factor (HIF-1α) as a key transcription factor i...

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Huvudupphov: Joanna Moczydlowska, Wojciech Miltyk, Adam Hermanowicz, Dariusz M. Lebensztejn, Jerzy A. Palka, Wojciech Debek
Materialtyp: Artigo
Språk:Inglês
Utgiven: Taylor & Francis Group 2017-01-01
Serie:Journal of Investigative Surgery
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Länkar:http://dx.doi.org/10.1080/08941939.2016.1183734
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