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Paracrine IL-33 stimulation enhances lipopolysaccharide-mediated macrophage activation.

<h4>Background</h4>IL-33, a member of the IL-1 family of cytokines, provokes Th2-type inflammation accompanied by accumulation of eosinophils through IL-33R, which consists of ST2 and IL-1RAcP. We previously demonstrated that macrophages produce IL-33 in response to LPS. Some immune responses were s...

Ausführliche Beschreibung

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Hauptverfasser: Tatsukuni Ohno, Keisuke Oboki, Hideaki Morita, Naoki Kajiwara, Ken Arae, Shizuko Tanaka, Masako Ikeda, Motoyasu Iikura, Taishin Akiyama, Jun-ichiro Inoue, Kenji Matsumoto, Katsuko Sudo, Miyuki Azuma, Ko Okumura, Thomas Kamradt, Hirohisa Saito, Susumu Nakae
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2011-04-01
Schriftenreihe:PLoS ONE
Online-Zugang:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21494550/?tool=EBI
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