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KRAS mutation status concordance between the primary tumor and the corresponding metastasis in patients with rectal cancer.

<h4>Introduction</h4>Oncogenic mutation within the KRAS gene represents a negative predictor for treatment response to anti-epidermal growth factor receptor (EGFR) in patients with colorectal cancer. Recently, we have shown no relevant heterogeneity for KRAS mutation status within and between pre- a...

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Hlavní autoři: Peter Jo, Markus Bernhardt, Manuel Nietert, Alexander König, Azadeh Azizian, Markus A Schirmer, Marian Grade, Julia Kitz, Kirsten Reuter-Jessen, Michael Ghadimi, Philipp Ströbel, Hans-Ulrich Schildhaus, Jochen Gaedcke
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2020-01-01
Edice:PLoS ONE
On-line přístup:https://doi.org/10.1371/journal.pone.0239806
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