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Green metrics and quality by design tool evaluated UPLC content determination method for Sparsentan in formulation sample

Sparsentan (SRN) is an endothelin and angiotensin II receptor antagonist indicated to reduce proteinuria in adults with primary immunoglobulin a nephropathy at task of rapid disease progression. In this study, we developed and validated a method to determine SRN in pharmaceutical dosage form using a...

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Principais autores: Satyajit Raj Nethekar, Phani Raja Kanuparthy, Bhukya Vijay Nayak, Leela Prasad Kowtharapu, Rambabu Gundla, Naresh Kumar Katari, Sreekantha B Jonnalagadda
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2025-12-01
Serier:Green Analytical Chemistry
Fag:
SRN
UPLC
QbD
ICH
Green chemistry
Online adgang:http://www.sciencedirect.com/science/article/pii/S2772577425001065
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