Prevalence of ExoY Activity in Pseudomonas aeruginosa Reference Panel Strains and Impact on Cytotoxicity in Epithelial Cells

ExoY is among the effectors that are injected by the type III secretion system (T3SS) of Pseudomonas aeruginosa into host cells. Inside eukaryotic cells, ExoY interacts with F-actin, which stimulates its potent nucleotidyl cyclase activity to produce cyclic nucleotide monophosphates (cNMPs). ExoY ha...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Hazel Silistre, Dorothée Raoux-Barbot, Federica Mancinelli, Flora Sangouard, Alice Dupin, Alexander Belyy, Vincent Deruelle, Louis Renault, Daniel Ladant, Lhousseine Touqui, Undine Mechold
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2021-10-01
Edice:	Frontiers in Microbiology
Témata:	ExoY nucleotidyl cyclase Pseudomonas aeruginosa cystic fibrosis cGMP
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fmicb.2021.666097/full
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!