Acquired ASXL1 mutations are common in patients with inherited GATA2 mutations and correlate with myeloid transformation
Inherited or sporadic heterozygous mutations in the transcription factor GATA2 lead to a clinical syndrome characterized by non-tuberculous mycobacterial and other opportunistic infections, a severe deficiency in monocytes, B cells and natural killer cells, and progression from a hypocellular myelod...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Ferrata Storti Foundation
2014-02-01
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| Schriftenreihe: | Haematologica |
| Online-Zugang: | https://haematologica.org/article/view/6926 |
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