Activation of the Thiazide-Sensitive Sodium-Chloride Cotransporter by Beta3-Adrenoreceptor in the Distal Convoluted Tubule

We previously showed that the beta-3 adrenergic receptor (BAR3) is expressed in most segments of the nephron where its agonism promotes a potent antidiuretic effect. We localized BAR3 in distal convoluted tubule (DCT) cells expressing the thiazide-sensitive sodium-chloride cotransporter (NCC). Aim o...

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Ngā kaituhi matua:	Serena Milano, Monica Carmosino, Andrea Gerbino, Ilenia Saponara, Dominga Lapi, Massimo Dal Monte, Paola Bagnoli, Maria Svelto, Giuseppe Procino
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	Frontiers Media S.A. 2021-08-01
Rangatū:	Frontiers in Physiology
Ngā marau:	beta3-adrenoreceptor distal convoluted tubule thiazide-sensitive Na-Cl cotransporter sympathetic regulation sodium-chloride cotransporter
Urunga tuihono:	https://www.frontiersin.org/articles/10.3389/fphys.2021.695824/full
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