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Whole-genome reference of Dirofilaria immitis from Australia to determine single nucleotide polymorphisms associated with macrocyclic lactone resistance in the USA

For the past 30 years, chemoprophylaxis with macrocyclic lactone (ML) anthelmintics has been the primary strategy for canine heartworm (Dirofilaria immitis) control in both the USA and Australia. ML-resistant D. immitis isolates have been confirmed to exist in the USA and studies have shown that 42...

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Main Authors: Daisy Ching-Wai Lau, Stephanie McLeod, Sara Collaery, Selina Peou, Andy Truc Tran, Michelle Liang, Jan Šlapeta
Format: Artigo
Language:Inglês
Published: Elsevier 2021-01-01
Series:Current Research in Parasitology and Vector-Borne Diseases
Subjects:
Dirofilaria immitis
Canine heartworm
Sydney
Resistance
SNP
Genomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2667114X21000017
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