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Clinical approach for managing patients with unexpected CDH1 mutations: A case report

Abstract Background Hereditary diffuse gastric cancer (HDGC) (OMIM# 137215) is an autosomal dominant cancer syndrome associated with CDH1 (OMIM# 192090) mutations. Prophylactic total gastrectomy (PTG) is the most recommended preventive treatment when a pathogenic mutation is found. However, the incr...

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Principais autores: Yago Garitaonaindia, Miriam Méndez, Fátima Valentín, Lourdes Gutiérrez, Alberto Herreros deTejada, Antonio Sánchez Ruiz, Mariano Provencio, Atocha Romero
Formato: Artigo
Idioma:Inglês
Publicado: Wiley 2024-07-01
Series:Molecular Genetics & Genomic Medicine
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Acceso en liña:https://doi.org/10.1002/mgg3.2496
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