Detecting patterns of accessory genome coevolution in Staphylococcus aureus using data from thousands of genomes

Abstract Bacterial genomes exhibit widespread horizontal gene transfer, resulting in highly variable genome content that complicates the inference of genetic interactions. In this study, we develop a method for detecting coevolving genes from large datasets of bacterial genomes based on pairwise com...

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Detalles Bibliográficos

Principais autores:	Rohan S Mehta, Robert A Petit, Timothy D Read, Daniel B Weissman
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2023-06-01
Series:	BMC Bioinformatics
Assuntos:	Genomics Genetic interaction Horizontal gene transfer Staphylococcus aureus Software Microbial genomics
Acceso en liña:	https://doi.org/10.1186/s12859-023-05363-4
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