4-phenylbutyric acid promotes migration of gastric cancer cells by histone deacetylase inhibition-mediated IL-8 upregulation

Histone acetylation is regulated by histone acetyltransferases (HATs) and histone deacetylases (HDACs). It is associated with gene transcription and expression. 4-Phenylbutyric acid (4-PBA), an HDAC inhibitor (HDACi), can inhibit cancer cell proliferation by increasing the level of histone acetylati...

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Detalhes bibliográficos

Principais autores:	Xiaonan Shi, Libao Gong, Yunpeng Liu, Kezuo Hou, Yibo Fan, Ce Li, Ti Wen, Xiujuan Qu, Xiaofang Che
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis Group 2020-07-01
coleção:	Epigenetics
Assuntos:	4-pba histone deacetylase inhibitor histone acetylation il-8 emt gastric cancer cell
Acesso em linha:	http://dx.doi.org/10.1080/15592294.2019.1700032
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