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Kampo formula hochu-ekki-to (Bu-Zhong-Yi-Qi-Tang, TJ-41) ameliorates muscle atrophy by modulating atrogenes and AMPK in vivo and in vitro

Abstract Background Muscle disuse results in loss of skeletal muscle mass and function. Hochu-ekki-to (TJ-41; Bu-Zhong-Yi-Qi-Tang in Chinese) is an herbal medicinal formulation used to treat patients with frailty, fatigue and appetite loss. It has been suggested that two atrogenes, atrogin-1 and mus...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Mitsutaka Yakabe, Tatsuya Hosoi, Hiroko Sasakawa, Masahiro Akishita, Sumito Ogawa
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2022-12-01
Schriftenreihe:BMC Complementary Medicine and Therapies
Schlagworte:
TJ-41
Tail-suspension
atrogin-1
AMPK
Herbal medicine
Online-Zugang:https://doi.org/10.1186/s12906-022-03812-w
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