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Identification of the Anti-sickling Activity of Anogeissus leiocarpus and In Silico Investigation of Some of Its Phytochemicals

Abstract Background: The anti-sickling activity of Anogeissus leiocarpus, a plant used for managing sickle cell disease (SCD), has been previously proven. Objectives: This study investigated the anti-sickling mechanism of A. leiocarpus by probing its effects on Gardos channel (KCNN4), erythropoie...

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Principais autores: Taiwo O. Elufioye, Babatunde M. Williams, Mojisola C. Cyril-Olutayo
פורמט: Artigo
שפה:Inglês
יצא לאור: Hamadan University of Medical Sciences 2020-06-01
סדרה:Avicenna Journal of Medical Biochemistry
נושאים:
sickle cell anaemia
anogeissus leiocarpus
gardos channel
erythropoiesis
mechanism of action
גישה מקוונת:http://ajmb.umsha.ac.ir/PDF/ajmb-8-1.pdf
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