CRL2LRRC41-Mediated DDX5 Ubiquitination Enhances Interaction with ELAVL1 Preventing NOG mRNA Degradation and Sustaining Proliferation and Migration of Human Spermatogonial Stem Cell-Like Cell Line

Abstract Background Human spermatogonial stem cells (SSCs) exhibit a remarkable capacity for proliferation, crucial for sustaining spermatogenesis throughout life. While the Cullin-RING E3 ubiquitin ligase 2 (CRL2) complex is known to regulate various cellular functions, its precise role in human SS...

Ful tanımlama

Detaylı Bibliyografya

Asıl Yazarlar:	Bing Jiang, Kehan Wang, Haoyue Hu, Wenxin Gao, Cong Shen, Xia Chen, Xiaoyan Huang, Jun Yu, Yibo Wu, Bo Zheng
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	BMC 2025-08-01
Seri Bilgileri:	BMC Biology
Konular:	LRRC41 DDX5 ELAVL1 Ubiquitination Spermatogonial Stem Cells
Online Erişim:	https://doi.org/10.1186/s12915-025-02363-z
Etiketler:	Etiketle Etiket eklenmemiş, İlk siz ekleyin!