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Knock Out of CGN and CGNL1 in MDCK Cells Affects Claudin-2 but Has a Minor Impact on Tight Junction Barrier Function

Cingulin (CGN) and paracingulin (CGNL1) are cytoplasmic proteins of tight junctions (TJs), where they play a role in tethering ZO-1 to the actomyosin and microtubule cytoskeletons. The role of CGN and CGNL1 in the barrier function of epithelia is not completely understood. Here, we analyzed the effe...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Marine Maupérin, Ali Sassi, Isabelle Méan, Eric Feraille, Sandra Citi
Hōputu: Artigo
Reo:Inglês
I whakaputaina: MDPI AG 2023-08-01
Rangatū:Cells
Ngā marau:
Urunga tuihono:https://www.mdpi.com/2073-4409/12/15/2004
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