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Pneumococcal VncR Strain-Specifically Regulates Capsule Polysaccharide Synthesis

Capsular polysaccharides (CPS), a major virulence factor in Streptococcus pneumoniae, become thicker during blood invasion while not during asymptomatic nasopharyngeal colonization. However, the underlying mechanism controlling this differential pneumococcal CPS regulation remain unclear. Here, we s...

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Main Authors: Prachetash Ghosh, Masaud Shah, Subramaniyam Ravichandran, Sang-Sang Park, Hamid Iqbal, Sangdun Choi, Kyeong Kyu Kim, Dong Kwon Rhee
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Microbiology
Subjects:
VncR
capsular polysaccharide
strain-specific
lactoferrin
Streptococcus pneumoniae
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.02279/full
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