Anti-Inflammatory, Analgesic and Antioxidant Potential of New (2<i>S</i>,3<i>S</i>)-2-(4-isopropylbenzyl)-2-methyl-4-nitro-3-phenylbutanals and Their Corresponding Carboxylic Acids through In Vitro, In Silico and In Vivo Studies

In the current study, a series of new (2<i>S</i>,3<i>S</i>)-2-(4-isopropylbenzyl)-2-methyl-4-nitro-3-phenylbutanals (<b>FM1-6</b>) with their corresponding carboxylic acid analogues (<b>FM7-12</b>) has been synthesized. Initially, the aldehydic derivatives were isolated in the diastereomeric form, a...

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Bibliografische Detailangaben

Hauptverfasser:	Fawad Mahmood, Jamshaid Ali Khan, Mater H. Mahnashi, Muhammad Saeed Jan, Muhammad Aamir Javed, Umer Rashid, Abdul Sadiq, Syed Shams ul Hassan, Simona Bungau
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2022-06-01
Schriftenreihe:	Molecules
Schlagworte:	Michael products anti-inflammatory antioxidant analgesic carrageenan COX-2
Online-Zugang:	https://www.mdpi.com/1420-3049/27/13/4068
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