Altered Immune Phenotypes and HLA-DQB1 Gene Variation in Multiple Sclerosis Patients Failing Interferon β Treatment

BackgroundInterferon beta (IFNβ) has been prescribed as a first-line disease-modifying therapy for relapsing-remitting multiple sclerosis (RRMS) for nearly three decades. However, there is still a lack of treatment response markers that correlate with the clinical outcome of patients.AimTo determine...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Priyanka Devi-Marulkar, Carolina Moraes-Cabe, Pascal Campagne, Béatrice Corre, Aida Meghraoui-Kheddar, Vincent Bondet, Alba Llibre, Darragh Duffy, Elisabeth Maillart, Caroline Papeix, Sandra Pellegrini, Frédérique Michel
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2021-05-01
coleção:	Frontiers in Immunology
Assuntos:	multiple sclerosis type I interferon T cells interferon-stimulated genes HLA class II genes immune phenotypes
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.628375/full
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!