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A modified BPaL regimen for tuberculosis treatment replaces linezolid with inhaled spectinamides

The Nix-TB clinical trial evaluated a new 6 month regimen containing three oral drugs; bedaquiline (B), pretomanid (Pa), and linezolid (L) (BPaL regimen) for the treatment of tuberculosis (TB). This regimen achieved remarkable results as almost 90% of the multidrug-resistant or extensively drug-resi...

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Автори: Malik Zohaib Ali, Taru S Dutt, Amy MacNeill, Amanda Walz, Camron Pearce, Ha Lam, Jamie S Philp, Johnathan Patterson, Marcela Henao-Tamayo, Richard Lee, Jiuyu Liu, Gregory T Robertson, Anthony J Hickey, Bernd Meibohm, Mercedes Gonzalez Juarrero
Формат: Artigo
Мова:Inglês
Опубліковано: eLife Sciences Publications Ltd 2024-10-01
Серія:eLife
Предмети:
Mycobacterium
tuberculosis
inhalation
spectinmaides
linezolid
bedaquiline/pretomanid
Онлайн доступ:https://elifesciences.org/articles/96190
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