SOCS-JAK-STAT inhibitors and SOCS mimetics as treatment options for autoimmune uveitis, psoriasis, lupus, and autoimmune encephalitis

Autoimmune diseases arise from atypical immune responses that attack self-tissue epitopes, and their development is intricately connected to the disruption of the JAK-STAT signaling pathway, where SOCS proteins play crucial roles. Conditions such as autoimmune uveitis, psoriasis, lupus, and autoimmu...

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Hlavní autoři:	Rahul Pandey, Marina Bakay, Hakon Hakonarson
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2023-10-01
Edice:	Frontiers in Immunology
Témata:	JAK-STAT inflammation autoimmunity SOCS (suppressor of cytokine signaling) psoriasis uveitis
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1271102/full
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