Relationship between localization on cellular membranes and cytotoxicity of Vibrio vulnificus hemolysin.

Vibrio vulnificus secretes a hemolysin/cytolysin (VVH) that induces cytolysis in target cells. A detergent resistant membrane domain (DRM) fraction of the cells after sucrose gradient centrifugation includes cholesterol-rich membrane microdomains which have been called "lipid rafts". It was reported...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Hiroyuki Sugiyama, Takashige Kashimoto, Shunji Ueno, Hayato Ehara, Toshio Kodama, Tetsuya Iida, Nobuyuki Susa
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Public Library of Science (PLoS) 2011-01-01
Schriftenreihe:	PLoS ONE
Online-Zugang:	http://europepmc.org/articles/PMC3197612?pdf=render
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