The Effect of Vicinal Difluorination on the Conformation and Potency of Histone Deacetylase Inhibitors
Histone deacetylase enzymes (HDACs) are potential targets for the treatment of cancer and other diseases, but it is challenging to design isoform-selective agents. In this work, we created new analogs of two established but non-selective HDAC inhibitors. We decorated the central linker chains of the...
I tiakina i:
| Ngā kaituhi matua: | , , , , , |
|---|---|
| Hōputu: | Artigo |
| Reo: | Inglês |
| I whakaputaina: |
MDPI AG
2021-06-01
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| Rangatū: | Molecules |
| Ngā marau: | |
| Urunga tuihono: | https://www.mdpi.com/1420-3049/26/13/3974 |
| Ngā Tūtohu: |
Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!
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