Treatment-Induced Gene Expression Changes in Metastatic Renal Cell Carcinoma: Insights from a Syngeneic Mouse Model

This study aimed to clarify the alterations in gene expression in metastatic renal cell carcinoma (mRCC) during disease progression and in response to treatment with immune checkpoint inhibitors using a syngeneic mouse mRCC model. RENCA cells were orthotopically implanted in BALB/c mice. Mice receiv...

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Autori principali:	Ko Okabe, Toshiaki Tanaka, Tetsuya Shindo, Yuki Kyoda, Sachiyo Nishida, Kohei Hashimoto, Ko Kobayashi, Naoya Masumori
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2025-07-01
Serie:	Current Oncology
Soggetti:	gene expression profiles immune checkpoint inhibitor metastatic renal cell carcinoma mouse model targeted therapy
Accesso online:	https://www.mdpi.com/1718-7729/32/7/391
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