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Development of inclusion complex based on cyclodextrin and oxazolidine derivative

Abstract Oxazolidine derivatives (OxD) have been described as third-line antibiotics and antitumoral agents. The inclusion complexes based on cyclodextrin could improve the solubility and bioavailability of these compounds. A novel synthetic OxD was used, and its inclusion complexes were based on 2-...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Rafael Ramos Silva, Cézar Augusto da Cruz Amorim, Maria do Carmo Alves Lima, Marcelo Montenegro Rabello, Marcelo Zaldini Hernandes, Moacyr Jesus Barreto de Melo Rêgo, Maira Galdino da Rocha Pitta, Maria Danielly Lima de Oliveira, César Augusto Souza de Andrade
Format: Artigo
Sprache:Inglês
Veröffentlicht: Universidade de São Paulo, Faculdade de Ciências Farmacêuticas 2023-06-01
Schriftenreihe:Brazilian Journal of Pharmaceutical Sciences
Schlagworte:
Oxazolidine
Cyclodextrin
Solubility
Modeling
Characterization
Online-Zugang:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502023000100388&tlng=en
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