Discovery of Molecular DNA Methylation-Based Biomarkers through Genome-Wide Analysis of Response Patterns to BCG for Bladder Cancer

Background: Bacillus Calmette-Guérin (BCG) immunotherapy, the standard adjuvant intravesical therapy for some intermediate and most high-risk non-muscle invasive bladder cancers (NMIBCs), suffers from a heterogenous response rate. Molecular markers to help guide responses are scarce and currently no...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Dafina Ilijazi, Walter Pulverer, Iris E. Ertl, Ursula Lemberger, Shoji Kimura, Mohammad Abufaraj, David D’Andrea, Benjamin Pradere, Andreas Bruchbacher, Anna Graf, Francesco Soria, Martin Susani, Andrea Haitel, Luca Molinaro, Armin Pycha, Evi Comploj, Stephan Pabinger, Andreas Weinhäusel, Gerda Egger, Shahrokh F. Shariat, Melanie R. Hassler
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2020-08-01
Schriftenreihe:	Cells
Schlagworte:	bladder cancer Bacillus Calmette-Guérin DNA methylation marker urothelial cancer Illumina MethylationEPIC BeadChip high-risk bladder cancer
Online-Zugang:	https://www.mdpi.com/2073-4409/9/8/1839
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