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The molecular chaperone Hsp90α is required for meiotic progression of spermatocytes beyond pachytene in the mouse.

The molecular chaperone Hsp90 has been found to be essential for viability in all tested eukaryotes, from the budding yeast to Drosophila. In mammals, two genes encode the two highly similar and functionally largely redundant isoforms Hsp90α and Hsp90β. Although they are co-expressed in most if not...

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Principais autores: Iwona Grad, Christopher R Cederroth, Joël Walicki, Corinne Grey, Sofia Barluenga, Nicolas Winssinger, Bernard De Massy, Serge Nef, Didier Picard
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2010-12-01
Serier:PLoS ONE
Online adgang:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21209834/pdf/?tool=EBI
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