Generation and Characterization of Anti-Filovirus Nucleoprotein Monoclonal Antibodies

Filoviruses cause lethal hemorrhagic fever in humans. The filovirus nucleoprotein (NP) is expressed in high abundance in infected cells and is essential for virus replication. To generate anti-filovirus monoclonal antibodies (mAbs) against the NP, mice were immunized with peptides known as B-cell ep...

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Autors principals:	Md Niaz Rahim, Min Wang, Tong Wang, Shihua He, Bryan D. Griffin, Darwyn Kobasa, Ruifu Yang, Zongmin Du, Xiangguo Qiu
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2019-03-01
Col·lecció:	Viruses
Matèries:	mAb (monoclonal antibody) Ebola (EBOV) Sudan (SUDV) Bundibugyo (BDBV) Marburg (MARV) Tai Forest (TAFV) Reston (RESTV) viruses
Accés en línia:	http://www.mdpi.com/1999-4915/11/3/259
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