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BRET biosensors to study GPCR biology, pharmacology and signal transduction

Bioluminescence Resonance Energy Transfer (BRET) based biosensors have been extensively used over the last decade to study protein-protein interactions and intracellular signal transduction in living cells. In this review, we discuss the various BRET biosensors that have been developed to investigat...

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Kaydedildi:
Asıl Yazarlar: Ali eSalahpour, Stefano eEspinoza, Bernard eMasri, Vincent eLam, Lawrence eBarak, Raul R Gainetdinov
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2012-08-01
Seri Bilgileri:Frontiers in Endocrinology
Konular:
Arrestins
GPCRs
BRET
cAMP
GRKs
Screening assay
Online Erişim:http://journal.frontiersin.org/Journal/10.3389/fendo.2012.00105/full
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