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Autophagy-dependent and -independent modulation of oxidative and organellar stress in the diabetic heart by glucose-lowering drugs

Abstract Autophagy is a lysosome-dependent intracellular degradative pathway, which mediates the cellular adaptation to nutrient and oxygen depletion as well as to oxidative and endoplasmic reticulum stress. The molecular mechanisms that stimulate autophagy include the activation of energy deprivati...

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Detaylı Bibliyografya
Yazar: Milton Packer
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BMC 2020-05-01
Seri Bilgileri:Cardiovascular Diabetology
Konular:
Online Erişim:http://link.springer.com/article/10.1186/s12933-020-01041-4
Etiketler: Etiketle
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