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Development of an In Vitro Methodology to Assess the Bioequivalence of Orally Disintegrating Tablets Taken without Water

To assess the probability of bioequivalence (BE) between orally disintegrating tablets (ODTs) taken without water and conventional tablets (CTs) taken with water, an in vitro biorelevant methodology was developed using the BE Checker, which reproduces fluid shifts in the gastrointestinal tract and d...

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Principais autores: Toshihide Takagi, Takato Masada, Keiko Minami, Makoto Kataoka, Shinji Yamashita
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2023-08-01
coleção:Pharmaceutics
Assuntos:
bioequivalence
orally disintegrating tablets
biorelevant dissolution
gastric emptying
gastrointestinal physiology
drug permeation
Acesso em linha:https://www.mdpi.com/1999-4923/15/9/2192
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