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Cloning and Characterization of Yak <i>DHODH</i> Gene and Its Functional Studies in a Bisphenol S-Induced Ferroptosis Model of Fetal Fibroblasts

Dihydroorotate dehydrogenase (DHODH) is a rate-limiting enzyme of <i>de novo</i> biosynthesis of pyrimidine. Although the involvement of DHODH in resisting ferroptosis has been successively reported in recent years, which greatly advanced the understanding of the mechanism of programmed cell death (...

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Main Authors: Hongmei Xu, Yueyue Li, Qiao Li, Zifeng Ma, Shi Yin, Honghong He, Yan Xiong, Xianrong Xiong, Daoliang Lan, Jian Li, Wei Fu
Format: Artigo
Language:Inglês
Published: MDPI AG 2023-12-01
Series:Animals
Subjects:
yak
<i>DHODH</i> gene
fetal fibroblasts
ferroptosis
Bisphenol S
Online Access:https://www.mdpi.com/2076-2615/13/24/3832
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