Strategy for drug repurposing in fibroadipogenic replacement during muscle wasting: application to duchenne muscular dystrophy

BackgroundUnderstanding the cell functionality during disease progression or drugs’ mechanism are major challenges for precision medicine. Predictive models describing biological phenotypes can be challenging to obtain, particularly in scenarios where sample availability is limited, such as in the c...

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Autors principals:	Izzy Matthews, Priyanka Mehra, Xavier Suárez-Calvet, Patricia Piñol-Jurado, Dan Cox, Vellia Justian, Ana Carrasco-Rozas, Zoe Laidler, Andrew Bowey, Paul Rushton, Susana López-Fernández, Jordi Díaz-Manera, Esther Fernández-Simón
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2025-03-01
Col·lecció:	Frontiers in Cell and Developmental Biology
Matèries:	muscle dystrophies fibro-adipogenic progenitor cells fibrosis adipogenesis sarcopenia cachexia
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fcell.2025.1505697/full
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