Gamma Interferon Is Required for <italic toggle="yes">Chlamydia</italic> Clearance but Is Dispensable for T Cell Homing to the Genital Tract

ABSTRACT While there is no effective vaccine against Chlamydia trachomatis infection, previous work has demonstrated the importance of C. trachomatis-specific CD4+ T cells (NR1 T cells) in pathogen clearance. Specifically, NR1 T cells have been shown to be protective in mice, and this protection dep...

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Autori principali:	Jennifer D. Helble, Rodrigo J. Gonzalez, Ulrich H. von Andrian, Michael N. Starnbach
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology 2020-04-01
Serie:	mBio
Soggetti:	Chlamydia IFN-γ T cells genital tract immunity interferons mucosal immunity
Accesso online:	https://journals.asm.org/doi/10.1128/mBio.00191-20
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