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Formulation, characterization, cytotoxicity and Salmonella/microsome mutagenicity (Ames) studies of a novel 5-fluorouracil derivative

5-Fluorouracil is one of the first line drugs for the systemic therapy of solid tumors like breast, colorectal, oesophageal, stomach, pancreatic, head and neck.It could be shown that sugars can improve the absorption across cell membranes and can help to bypass some pharmacokinetic problems. Carbohy...

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Auteurs principaux: Çinel Köksal Karayildirim, Mustafa Kotmakçi, Erkan Halay, Kadir Ay, Yücel Başpinar
Format: Artigo
Langue:Inglês
Publié: Springer 2018-03-01
Collection:Saudi Pharmaceutical Journal
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Accès en ligne:http://www.sciencedirect.com/science/article/pii/S1319016418300045
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