Biomimetic nanoimmunotherapy boosts spatiotemporal PANoptosis and reshapes desmoplastic tumor microenvironment

Summary: Dendritic cell (DC)-based vaccines for solid tumors face major challenges, including limited tumor-specific antigens and immunosuppressive stroma. Here, we present a therapeutic nanovaccine (UCNP@MOF@MI@FM [UMMF]) composed of a DC/tumor fused cytomembrane-coated UCNP@MOF nanoparticle, co-lo...

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Autori principali:	Hui Huang, Zebin Xiao, Wei Feng, Xinran Song, Liang Chen, Lili Huang, Li Ding, Yu Chen
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2025-09-01
Serie:	Cell Reports Medicine
Soggetti:	immunotherapy biomimetic nanomaterials nanovaccine PANoptosis tumor microenvironment
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2666379125003854
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