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Deciphering the glioblastoma microenvironmental landscape with multi-modal radiogenomics to guide prognosis and personalized therapy

Abstract Background Glioblastoma (GBM) is a highly heterogeneous and treatment-refractory tumor, where the tumor microenvironment (TME) plays a central role in shaping progression and therapeutic response. However, the molecular and cellular basis of TME-linked heterogeneity, and how it can be captu...

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Autori principali: Hongying Zhao, Kailai Liu, Marui Guan, Xun Tang, Yangxinyue Zheng, Hongzheng Yu, Shangwei Ning, Li Wang
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2026-05-01
Serie:Journal of Translational Medicine
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Accesso online:https://doi.org/10.1186/s12967-026-08226-7
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