Ectopic Expression of a Truncated Isoform of Hair Keratin 81 in Breast Cancer Alters Biophysical Characteristics to Promote Metastatic Propensity

Abstract Keratins are an integral part of cell structure and function. Here, it is shown that ectopic expression of a truncated isoform of keratin 81 (tKRT81) in breast cancer is upregulated in metastatic lesions compared to primary tumors and patient‐derived circulating tumor cells, and is associat...

Descrición completa

Detalles Bibliográficos

Principais autores:	Diane S. Kang, Aidan Moriarty, Yiru Jess Wang, Amal Thomas, Jia Hao, Bret A. Unger, Remi Klotz, Shamim Ahmmed, Yonatan Amzaleg, Stuart Martin, Siva Vanapalli, Ke Xu, Andrew Smith, Keyue Shen, Min Yu
Formato:	Artigo
Idioma:	Inglês
Publicado:	Wiley 2024-02-01
Series:	Advanced Science
Assuntos:	biophysical properties breast cancer circulating tumor cells keratins metastasis truncated isoform
Acceso en liña:	https://doi.org/10.1002/advs.202300509
Tags:	Engadir etiqueta Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!