Screening of drugs to treat 8p11 myeloproliferative syndrome using patient-derived induced pluripotent stem cells with fusion gene CEP110-FGFR1.

Induced pluripotent stem (iPS) cells provide powerful tools for studying disease mechanisms and developing therapies for diseases. The 8p11 myeloproliferative syndrome (EMS) is an aggressive chronic myeloproliferative disorder (MPD) that is caused by constitutive activation of fibroblast growth fact...

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Auteurs principaux:	Shohei Yamamoto, Makoto Otsu, Emiko Matsuzaka, Chieko Konishi, Haruna Takagi, Sachiyo Hanada, Shinji Mochizuki, Hiromitsu Nakauchi, Kohzoh Imai, Kohichiro Tsuji, Yasuhiro Ebihara
Format:	Artigo
Langue:	Inglês
Publié:	Public Library of Science (PLoS) 2015-01-01
Collection:	PLoS ONE
Accès en ligne:	http://europepmc.org/articles/PMC4372437?pdf=render
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