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PTEN modulates urinary tract infection susceptibility and shapes urothelial antibacterial defenses

This study reveals that PTEN modulates bladder urothelial immunity by regulating Akt, NFκB, and FAK signaling, shaping susceptibility to urinary tract infection. Despite advancements in our understanding of urinary tract infection (UTI) pathogenesis, UTIs remain a leading cause of morbidity, partly...

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Autori principali: Aaron Simoni, M Skye Bochter, Sarah Linn-Peirano, Kristin Salamon, Brian Becknell, Hanna Cortado, Ashley R Jackson, Laura Schwartz, John David Spencer
Natura: Artigo
Lingua:Inglês
Pubblicazione: Life Science Alliance LLC 2025-10-01
Serie:Life Science Alliance
Accesso online:https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.202503292
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