Concurrent expression of HP-NAP enhances antitumor efficacy of oncolytic vaccinia virus but not for Semliki Forest virus

Oncolytic viruses (OVs) represent promising therapeutic agents for cancer therapy by selective oncolysis and induction of anti-tumor immunity. OVs can be engineered to express tumor-associated antigens and immune-modulating agents to provoke stronger antitumor immunity. Here, we engineered vaccinia...

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Autors principals:	Jing Ma, Chuan Jin, Matko Čančer, Hai Wang, Mohanraj Ramachandran, Di Yu
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2021-06-01
Col·lecció:	Molecular Therapy: Oncolytics
Matèries:	oncolytic virus Semliki Forest virus vaccinia virus NAP neutrophil-activating protein immunotherapy
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S2372770521000668
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