Inhibitory Effects of Citrus-Derived Flavonoids Hesperidin and Hesperetin on SARS-CoV-2 Spike-Mediated Syncytia Formation Using In Vitro Cell Model

Purpose: SARS-CoV-2 infection may lead to a worse prognosis in COVID-19 patients by inducing syncytia formation which implies intercellular transmission and immune evasion. Hesperidin (HSD) and hesperetin (HST) are two citrus flavonoids that demonstrate the potential to interfere with spike/human an...

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Detalhes bibliográficos

Principais autores:	Dennaya Kumara, Hayfa Salsabila Harsan, Endah Puji Septisetyani, Pekik Wiji Prasetyaningrum, Komang Alit Paramitasari, Mukh Syaifudin, Okid Parama Astirin, Muthi Ikawati, Edy Meiyanto
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Tabriz University of Medical Sciences 2025-07-01
coleção:	Advanced Pharmaceutical Bulletin
Assuntos:	covid-19 citrus flavonoids sars-cov-2 syncytia
Acesso em linha:	https://apb.tbzmed.ac.ir/PDF/apb-15-416.pdf
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