Novel lactotransferrin-derived synthetic peptides suppress cariogenic bacteria in vitro and arrest dental caries in vivo: [Novel lactotransferrin-derived anticaries peptides]

Objectives: The aim of the study was to design and synthesise novel lactotransferrin-derived antimicrobial peptides (AMPs) with enhanced antibacterial activity against cariogenic bacteria. Methods: We obtained the LF-1 (WKLLRKAWKLLRKA) and LF-2 (GKLIWKLLRKAWKLLRKA) AMPs, based on the N-terminal func...

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Автори:	Junyuan Luo, Zening Feng, Wentao Jiang, Xuelian Jiang, Yue Chen, Xiaohui Lv, Linglin Zhang
Формат:	Artigo
Мова:	Inglês
Опубліковано:	Taylor & Francis Group 2021-01-01
Серія:	Journal of Oral Microbiology
Предмети:	antimicrobial peptide biofilm dental caries lactotransferrin rat streptococcus mutans
Онлайн доступ:	http://dx.doi.org/10.1080/20002297.2021.1943999
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