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The Interaction Between <i>Echinococcus multilocularis</i> Calreticulin S-Domain and Human Complement C1q Inhibits C1q-Dependent Immune Functions

<i>Em</i>CRT is a calreticulin secreted by <i>Echinococcus multilocularis</i> during its infection in host, playing an important role in evading host immune attack as a survival strategy. Our previous study has demonstrated that recombinant <i>Em</i>CRT (r<i>Em</i>CRT) was able to bind to C1q and le...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Meng Xia, Yinghui Song, Xiaofang Dong, Li Gu, Yishuo Wang, Wen Sun, Bin Zhan, Yan Yan, Limei Zhao
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2026-04-01
Schriftenreihe:Pathogens
Schlagworte:
<i>Echinococcus multilocularis</i>
calreticulin
binding site
S-domain
macrophages
immune evasion
Online-Zugang:https://www.mdpi.com/2076-0817/15/4/427
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