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Minnelide: a novel therapeutic that promotes apoptosis in non-small cell lung carcinoma in vivo.

BACKGROUND:Minnelide, a pro-drug of triptolide, has recently emerged as a potent anticancer agent. The precise mechanisms of its cytotoxic effects remain unclear. METHODS:Cell viability was studied using CCK8 assay. Cell proliferation was measured real-time on cultured cells using Electric Cell Subs...

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Principais autores: Ilona Rousalova, Sulagna Banerjee, Veena Sangwan, Kristen Evenson, Joel A McCauley, Robert Kratzke, Selwyn M Vickers, Ashok Saluja, Jonathan D'Cunha
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2013-01-01
coleção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC3797124?pdf=render
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