Plasma Prekallikrein: Its Role in Hereditary Angioedema and Health and Disease
Plasma prekallikrein (PK) has a critical role in acute attacks of hereditary angioedema (HAE). Unlike C1 inhibitor, its levels fall during HAE attacks with resultant cleaved high-molecular-weight kininogen. Cleavage of high-molecular-weight kininogen liberates bradykinin, the major biologic peptide...
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| Автор: | |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
Frontiers Media S.A.
2018-01-01
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| Серія: | Frontiers in Medicine |
| Предмети: | |
| Онлайн доступ: | http://journal.frontiersin.org/article/10.3389/fmed.2018.00003/full |
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