Injectable nanosuspension of docetaxel-loaded biodegradable periodic mesoporous Organosilica: A stable formulation with enhanced anticancer efficacy

Current intravenous docetaxel (DTX) formulations often contain excipients like polysorbate 80 and high-dose ethanol, which are associated with severe adverse effects and compound DTX's inherent systemic toxicity. This study addresses these limitations by developing a novel injectable nanosuspension...

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Autors principals:	Van-Ha Nguyen, Huiping Huang, Dang-Khoa Nguyen, Minh-Quan Le, Linh Ho Thuy Nguyen, Thang Bach Phan, Minh-Tri Le, Tan Le Hoang Doan
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2026-06-01
Col·lecció:	Journal of Science: Advanced Materials and Devices
Matèries:	Docetaxel Biodegradable periodic mesoporous organosilica Nanosuspension Drug delivery Polymer coating Stability
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S2468217926000535
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