Two subtypes of cutaneous melanoma with distinct mutational signatures and clinico-genomic characteristics

Background: To decipher mutational signatures and their associations with biological implications in cutaneous melanomas (CMs), including those with a low ultraviolet (UV) signature.Materials and Methods: We applied non-negative matrix factorization (NMF) and unsupervised clustering to the 96-class...

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Detalhes bibliográficos

Principais autores:	Yoon-Seob Kim, Minho Lee, Yeun-Jun Chung
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2022-09-01
coleção:	Frontiers in Genetics
Assuntos:	cutaneous melanoma mutational signature next generation seqencing ultraviolet melanoma
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fgene.2022.987205/full
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