Geranylgeraniol Modulates Inflammatory and Metabolic Pathways but Not IgD Biology in Mevalonate Kinase Deficiency
ObjectivesMevalonate kinase deficiency (MKD) is a metabolic disorder caused by a block in the mevalonate pathway, leading to impaired synthesis of cholesterol and isoprenoids. Clinically, MKD presents with recurrent inflammatory attacks. A characteristic feature is elevated serum IgD, although the u...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Rockefeller University Press
2026-05-01
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| Edice: | Journal of Human Immunity |
| On-line přístup: | https://rupress.org/jhi/article/2/CIS2026/eCIS2026abstract.64/281975/Geranylgeraniol-Modulates-Inflammatory-and |
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