Genetic disruption of the circadian gene Bmal1 in the intestinal epithelium reduces colonic inflammation
Abstract Disruption of the circadian clock is associated with the development of inflammatory bowel disease (IBD), but the underlying mechanisms remain unclear. Here, we observe that mice in the early active phase (Zeitgeber time 12, ZT12) of the circadian clock are more tolerant to dextran sodium s...
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| Principais autores: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Springer Nature
2025-04-01
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| Series: | EMBO Reports |
| Assuntos: | |
| Acceso en liña: | https://doi.org/10.1038/s44319-025-00464-y |
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